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ISC (CISCE) Class 12 Biology syllabus

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5 chapters10 topics

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Previous year question papers

Free, official past papers for ISC (CISCE).

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Important topics

Topics worth extra focus, based on real exam history, not a guess.

  • Human Reproduction (menstrual cycle, hormone regulation, placenta)(Reproduction)

    Oswaal Books' ISC 2026 board-exam-prep article flags this as a frequent source of diagrammatic questions.

  • Mendelian Inheritance, Dihybrid Crosses, Chromosomal Disorders(Genetics and Evolution)

    Oswaal Books names this as recurring content within Genetics and Evolution, which it calls the highest-weightage unit (though this conflicts with the official CISCE marks table, see Reproduction entry above).

  • DNA Replication, Transcription and Translation (Molecular Basis of Inheritance)(Genetics and Evolution)

    Oswaal Books names this a recurring diagram-based long-answer topic.

  • Genetic Engineering, Recombinant DNA Technology, PCR(Biotechnology)

    Oswaal Books calls Biotechnology content "direct and predictable" in ISC board exams.

  • Ecosystem Structure, Energy Flow and Biodiversity Conservation(Ecology and Environment)

    Oswaal Books states this topic "consistently" appears in ISC Biology board papers.